Fig. 11.

Migration and invasion experiments on LN229 cells and U87-MG cells after overexpression of TGFBI and pretreatment with FAK inhibitors. (A) Representative images of migration experiments and the number of transmembrane cells. (**P < 0.01, ***P < 0.001, ****P < 0.0001, n = 3, Student t test). (B) Representative images of invasion experiments and the number of transmembrane cells. (**P < 0.01, ***P < 0.001, ****P < 0.0001, n = 3, Student t test). Vector: transfect empty plasmid. OE-TGFBI: transfect TGFBI overexpression plasmid. Vector + inhibitor: transfect empty plasmid and pretreatment with PF-573,228 for 1 h before the experiment. OE-TGFBI + inhibitor: transfect TGFBI overexpression plasmid and pretreatment with PF-573,228 for 1 h before the experiment. The magnification of the above image is 200×