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. 2024 Oct 26;25:383. doi: 10.1186/s12875-024-02613-z

Table 1.

Characteristics of the subjects with hypothyroidism on thyroxine medication

Follow-Up TFTa
Total Under-replace Euthyroid Over-replace P-value
Total 5749 (100) 1694 (29.5) 3558 (61.9) 497 (8.6)
Age 62.1 (13.29) 62.25 (13.76) 62.22 (12.99) 60.79 (13.69) 0.07
Gender  < 0.001
 Female 4539 (79) 1273 (28) 2865 (63.1) 401 (8.8)
 Male 1210 (21) 421 (34.8) 693 (57.3) 96 (7.9)
Ethnicity  < 0.001
 Chinese 4583 (79.7) 1301 (28.4) 2906 (63.4) 376 (8.2)
 Malay 365 (6.3) 130 (35.6) 190 (52.1) 45 (12.3)
 Indian 572 (9.9) 199 (34.8) 321 (56.1) 52 (9.1)
 Other 229 (4) 64 (27.9) 141 (61.6) 24 (10.5)
BMIb  < 0.001
 Underweight 156 (4.6) 58 (37.2) 90 (57.7) 8 (5.1)
 Normal 1013 (29.8) 270 (26.7) 653 (64.5) 90 (8.9)
 Overweight 1323 (38.9) 368 (27.8) 836 (63.2) 119 (9)
 Obese 909 (26.7) 315 (34.7) 517 (56.9) 77 (8.5)

aThyroid function tests

bBMI Body Mass Index