Table 6.
Top 20 differentially common over-represented EV proteins vs. healthy control in the carcinoma cell lines
| Common over-represented proteins | |||||
|---|---|---|---|---|---|
| Accession number | Protein name | Protein abbreviation |
MTH52C Log2FC |
1305 Log2FC |
DT1406TB Log2FC |
| A0A8I3NGU2 | Folate_rec domain-containing protein | LOC476816 | 7.242 | 8.684 | 9.315 |
| A0A8P0TLW8 | Scavenger receptor cysteine rich family member with 5 domains | SSC5D | 8.289 | 10.690 | 5.018 |
| Q28275 | Fibronectin (Fragment) | FN1 | 4.837 | 6.517 | 10.712 |
| A0A8P0SNB9 | Biglycan | BGN | 4.906 | 7.438 | 8.390 |
| A0A8I3PAS0 | Hyaluronan and proteoglycan link protein 1 | HAPLN1 | 6.534 | 2.065 | 11.965 |
| A0A8I3MGS0 | 72 kDa type IV collagenase | MMP2 | 3.103 | 6.260 | 8.838 |
| A0A8I3Q318 | Complement factor I | CFI | 3.497 | 4.469 | 8.752 |
| A0A8I3MZE8 | GM2 ganglioside activator | GM2A | 4.393 | 5.453 | 6.426 |
| A0A8I3PHI4 | Fibronectin | FN1 | 3.907 | 4.087 | 7.910 |
| A0A8I3PMB5 | Secretogranin-3 | SCG3 | 4.982 | 2.825 | 7.256 |
| A0A8I3PPU8 | Thrombospondin 1 | THBS1 | 1.870 | 7.201 | 5.508 |
| A0A8P0P6 × 6 | Cadherin-2 | CDH2 | 2.801 | 4.917 | 5.930 |
| A0A8I3Q5D9 | Procollagen C-endopeptidase enhancer 2 | PCOLCE2 | 2.813 | 3.477 | 7.098 |
| A0A8I3MTJ9 | Laminin subunit gamma 1 | LAMC1 | 3.385 | 5.938 | 3.625 |
| A0A8I3PM12 | L1 cell adhesion molecule | L1CAM | 1.683 | 7.241 | 3.972 |
| A0A8I3PNM0 | G_PROTEIN_RECEP_F3_4 domain-containing protein | GPRC5D | 1.755 | 6.742 | 3.767 |
| A0A8P0TM99 | Pleckstrin homology like domain family B member 2 | PHLDB2 | 2.235 | 6.263 | 3.720 |
| A0A8P0SGF7 | Hyaluronan and proteoglycan link protein 3 | HAPLN3 | 3.031 | 3.779 | 5.017 |
| A0A8I3NXQ5 | Ethylmalonyl-CoA decarboxylase | 3 SV | 1.567 | 4.820 | 5.429 |
| A0A8I3S4E2 | Versican | VCAN | 1.607 | 4.248 | 5.805 |
| Common under-represented proteins | |||||
| Accession number | Protein name | Protein abbreviation |
MTH52C Log2FC |
1305 Log2FC |
DT1406TB Log2FC |
| A0A8I3Q193 | Selenocysteine lyase | SCLY | -1.972 | -5.637 | -5.324 |
| A0A8I3NJ98 | N-sulfoglucosamine sulfohydrolase | SGSH | -2.091 | -4.984 | -4.477 |
| A0A8I3QBZ4 | Taxilin gamma | TXLNG | -0.878 | -4.915 | -5.585 |
| A0A8P0SNX6 | tRNA: m(4)X modification enzyme TRM13 | TRMT13 | -2.591 | -5.158 | -3.569 |
| A0A8P0TLB2 | UBX domain-containing protein 7 | UBXN7 | -2.140 | -4.895 | -3.880 |
| A0A8I3MKV2 | Malignant T-cell-amplified sequence | LOC487150 | -2.309 | -4.124 | -3.935 |
| A0A8I3PUG8 | TATA-box binding protein | TBP | -2.315 | -3.893 | -4.015 |
| A0A8I3RWI4 | Section 1 family domain containing 2 | SCFD2 | -2.539 | -2.898 | -4.163 |
| A0A8I3PMJ4 | DIS3-like exonuclease 2 | DIS3L2 | -3.638 | -2.854 | -2.612 |
| A0A8I3N7E1 | CTP synthase | CTPS1 | -2.172 | -3.350 | -3.558 |
| A0A8I3MKB3 | CYRIA-B_Rac1-bd domain-containing protein | CYFIP2 | -2.791 | -3.719 | -2.455 |
| A0A8I3RYJ8 | Lysine demethylase 2 A | KDM2A | -0.797 | -4.070 | -4.012 |
| A0A8I3RXS7 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 | DPH1 | -2.365 | -2.992 | -3.444 |
| A0A8I3RW28 | ASPSCR1 tether for SLC2A4, UBX domain containing | ASPSCR1 | -1.848 | -4.301 | -2.302 |
| A0A8I3RX66 | thioredoxin-disulfide reductase | TXNRD3 | -1.867 | -4.939 | -1.281 |
| A0A8I3NN15 | Small nuclear ribonucleoprotein Sm D1 | SNRPD1 | -0.857 | -4.393 | -2.586 |
| A0A8P0NJW0 | Metastasis associated 1 | MTA1 | -1.104 | -4.682 | -1.985 |
| A0A8I3S647 | Propionyl-CoA carboxylase alpha chain, mitochondrial | PCCA | -2.235 | -3.662 | -1.763 |
| P10463 | Calcyphosin | CAPS | -1.802 | -2.734 | -2.894 |
| A0A8P0SK07 | Complement component 1 Q subcomponent-binding protein, mitochondrial | C1QBP | -0.944 | -3.812 | -2.622 |