Table 5.
Pregnancy outcomes of embryo transfer cycles between the high-risk DOR group and NOR group after propensity score matching
| High-risk DOR | NOR | p | |
|---|---|---|---|
| No. of fresh and frozen cycles, n | 775 | 916 | |
| No. of patients, n | 603 | 603 | |
| No. of mean ETs in oocytes aspiration cycles, n, mean ± SD | 1.285±0.677 | 1.519±0.854 | <0.002 |
| Live birth rates per total ET cycles, %(n) | 45.9 (356/775) | 51.1 (468/916) | 0.035 |
| Cumulative live birth rates per oocytes aspiration cycles, % (n) | 59.0 (356/603) | 77.6 (468/603) | <0.001 |
| No. of D3 ET cycles，n (%) | 576 (74.3) | 636(69.4) | 0.027 |
| Endometrial thickness on ET day, mean ± SD | 10.50±2.00 | 10.45±1.99 | 0.700 |
| No. of transferred embryos in ET, mean ± SD | 1.88±0.33 | 1.95±0.22 | <0.001 |
| HCG positive rates per ET, % (n) | 57.5 (331/576) | 65.1 (414/636) | 0.007 |
| Clinical pregnancy rates per ET, % (n) | 50.5 (291/576) | 58.2 (370/636) | 0.008 |
| Ongoing pregnancy rates per ET, % (n) | 44.8 (258/576) | 52.7 (335/636) | 0.007 |
| Pregnancy loss rates per ET, % (n) | 13.5 (78/576) | 13.8 (88/636) | 0.933 |
| Live birth rates per ET, % (n) | 43.9 (253/576) | 51.3 (326/636) | 0.011 |
| HCG positive cases in D3 ET cycles, n | 331 | 414 | |
| Biochemical pregnancy rates per HCG-positives, % (n) | 9.4 (31/331) | 9.2 (38/414) | 0.998 |
| Ectopic pregnancy rates per HCG-positives, % (n) | 2.7 (9/331) | 1.4 (6/414) | 0.295 |
| Early miscarriage rates per HCG-positives, % (n) | 10.0 (33/331) | 8.5 (35/414) | 0.302 |
| Late miscarriage rates per HCG-positives, % (n) | 1.5 (5/331) | 2.2 (9/414) | 0.594 |
| Live birth rates per HCG-positives, % (n) | 76.4 (253/331) | 78.7 (326/414) | 0.479 |
| No. of D5/D6 ET cycles, n (%) | 199 (25.7) | 280 (30.6) | 0.027 |
| Endometrial thickness on ET day, mean ± SD | 9.94±1.76 | 10.16±1.91 | 0.205 |
| No. of transferred embryos in ETs, mean ± SD | 1.10±0.30 | 1.28±0.45 | <0.001 |
| HCG positive rates per ET, % (n) | 64.8 (129/199) | 68.6 (192/280) | 0.43 |
| Clinical pregnancy rates per ET, % (n) | 58.8 (117/199) | 59.6 (167/280) | 0.925 |
| Ongoing pregnancy rates per ET, % (n) | 52.3 (104/199) | 51.8 (145/280) | 0.926 |
| Pregnancy loss rates per ET, % (n) | 13.1 (26/199) | 17.9 (50/280) | 0.165 |
| Live birth rates per ET, % (n) | 51.8 (103/199) | 50.7 (142/280) | 0.853 |
| HCG-positive cases in D5/6 ET cycles, n | 129 | 192 | |
| Biochemical pregnancy rates per HCG-positives, % (n) | 7.00 (9/129) | 12.5 (24/192) | 0.134 |
| Ectopic pregnancy rates per HCG-positives, % (n) | 2.30 (3/129) | 0.50 (1/192) | 0.306 |
| Early miscarriage rates per HCG-positives, % (n) | 10.1 (13/129) | 11.5 (22/192) | 0.72 |
| Late miscarriage rates per HCG-positives, % (n) | 0.80 (1/129) | 1.60 (3/192) | 0.651 |
| Live birth rates per HCG-positives, % (n) | 79.8 (103/129) | 74.0 (142/192) | 0.232 |