Table 5.

Factors associated with loss to follow-up in multivariate analysis

Effect	Effect measure	Wald stat	OR	95% Cl	P
Intercept		983.944	0.011	0.008–0.014	<0.0001
Age	≤ 40 years	3.739	1.216	0.997–1.483	0.0532
Gender	Male	9.530	1.362	1.119–1.657	0.0020
GT3 infection	Yes	43.203	2.103	1.685–2.625	<0.0001
History of previous therapy	Naive	4.440	1.334	1.020–1.744	0.0351
HIV-coinfection	Yes	43.847	2.476	1.893–3.238	<0.0001
Depression	Yes	6.488	1.655	1.123–2.438	0.0109
Drug addiction	Yes	0.676	1.273	0.716–2.260	0.4110
Alcohol addiction	Yes	31.652	3.153	2.114–4.705	<0.0001
Other psychiatric disordersa	Yes	13.709	2.591	1.565–4.289	0.0002
Therapy course	Discontinuation	274.068	22.563	15.601–32.631	<0.0001
Serious AEs	Yes	3.265	1.818	0.951–3.477	<0.071

Abbreviations: AE adverse event, CI Confidence interval, GT genotype, HIV human immunodeficiency virus, OR Odds ratio, LTFU loss to follow-up, SVR sustained virological response

^aSchizophrenia, bipolar affective disorder, psychotic disorders, dissociative disorders, personality disorders