TABLE 2.
Univariate and multivariate logistic regression analysis of recurrent factors in LARC.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Age (years) | ||||
| ≥ 60 vs. < 60 | 0.849 (0.589–1.224) | 0.381 | ||
| Gender | ||||
| Male vs. female | 0.657 (0.447–0.965) | 0.032 | 0.819 (0.529–1.267) | 0.369 |
| TNM stage | ||||
| II vs. III | 0.950 (0.657–1.375) | 0.787 | ||
| BMI | ||||
| ≥ 20.28 vs. < 20.28 | 0.617 (0.398–0.957) | 0.031 | 0.641 (0.387–1.062) | 0.084 |
| PNI | ||||
| ≥ 52.5 vs. < 52.5 | 0.608 (0.390–0.947) | 0.028 | 0.558 (0.335–0.931) | 0.025 |
| CEA | ||||
| < 5 vs. ≥ 5 | 0.615 (0.424–0.892) | 0.010 | 0.879 (0.572–1.351) | 0.557 |
| MRF | ||||
| Yes vs. no | 1.837 (1.234–2.736) | < 0.001 | 1.152 (0.666–1.992) | 0.613 |
| EMVI | ||||
| Yes vs. no | 2.75 (1.850–4.784) | < 0.001 | 2.685 (1.410–5.114) | 0.003 |
| Vascular tumor thrombus | ||||
| Yes vs. no | 3.320 (2.261–4.876) | < 0.001 | 2.067 (1.318–3.243) | 0.002 |
| Perineural invasion | ||||
| Yes vs. no | 4.459 (3.014–6.598) | < 0.001 | 3.200 (2.038–5.024) | < 0.001 |
| Tumor deposit | ||||
| Yes vs. no | 2.388 (1.474–3.869) | < 0.001 | 1.732 (0.983–3.049) | 0.057 |
| Tumor size (cm) | ||||
| ≥ 4.8 vs. < 4.8 | 2.472 (1.698–3.598) | < 0.001 | 2.749 (1.782–4.240) | < 0.001 |
Abbreviations: BMI, body mass index; EMVI, extramural vascular invasion; MRF, mesorectal fascia invasion; PNI, prognostic nutritional index.