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. 2024 Sep 3;11(40):2405200. doi: 10.1002/advs.202405200

Table 1.

Concentration and physical behaviors of three nanosuspensions (F1–F3) in pH 4.5 and pH 7.4 buffers.

Formulation F1 (PLGA‐QTP) F2 (PLGA‐QM) F3 (QMN)
Concentration of QTP/QM [mg mL−1] 69.6 ± 1.2 109.5 ± 0.8 a ) 101.5 ± 1.4 b )
pH buffer pH 4.5 pH 7.4 pH 4.5 pH 7.4 pH 4.5 pH 7.4
Physical state graphic file with name ADVS-11-2405200-g010.jpg graphic file with name ADVS-11-2405200-g002.jpg graphic file with name ADVS-11-2405200-g004.jpg graphic file with name ADVS-11-2405200-g003.jpg graphic file with name ADVS-11-2405200-g007.jpg graphic file with name ADVS-11-2405200-g008.jpg
Suspended Suspended Suspended Suspended Suspended Nano‐aggregated
a)

QM concentration in F2 equivalent to 70.7 ± 0.5 mg mL−1 QTP

b)

QM concentration in F3 equivalent to 65.6 ± 0.9 mg mL−1 QTP. Data are expressed as mean ± standard deviation (n = 3).