Fig. 2.

Structural comparison with SV5 and hRSV F1 core structures. (A) Overlay of the hPIV3 solF0, SV5 F1 core, and hRSV core structures. The SV5 N1/C1 peptide complex is shown in pale red. The hRSV N57/C45 complex is shown in pale green. (B) Comparison of hydrophobic pocket interactions of hPIV3 residues I454 and I456 with those in SV5 and hRSV. The hPIV3 residues are shown in yellow, with the backbone trace of the C-terminal segment shown in blue. The hRSV residues are shown in pale green, and the SV5 residues are shown in pale red.