Houkin et al35 (1996) |
24 |
Single institution; All underwent STA-MCA bypass + EDAMS |
6.4 years |
25% decrease in moyamoya vessels; 12.5% rebleed |
Rebleed risk may be reduced by surgery |
Iwama et al36 (1997) |
45 |
Single institution; Bypass: 43, No bypass: 2 |
3.7 years |
60% decrease in moyamoya vessels; 20% rebleed (postop) |
Rebleed risk may be reduced by surgery |
Fujii et al37 (1997) |
290 |
Multicenter retrospective study; Bypass: 152, No bypass: 138 |
? |
Bypass: 19.1% rebleed No bypass: 28.3% rebleed |
Rebleed risk may be reduced by surgery |
Okada et al38 (1998) |
15 |
Single institution; All underwent STA-MCA bypass |
7.8 years |
60% decrease in moyamoya vessels; 6.7% perioperative bleed; 20% rebleed |
Rebleed risk may be reduced by surgery |
Yoshida et al39 (1999) |
28 |
Single institution; Revascularization: 10, No revascularization: 18 |
14.2 years |
Revascularization: 12.5% rebleed No revascularization: 38.5% rebleed |
Rebleed risk may be reduced by surgery |
Kawaguchi et al40 (2000) |
22 |
Single institution; STA-MCA bypass: 6, EDAS: 5, No revascularization:11 |
8 years |
STA-MCA bypass: 0% recurrent stroke EDAS: 60% recurrent stroke No revascularization: 54% recurrent stroke |
Rebleed risk reduced by bypass (p < 0.05) |