Table 1.
Comparison of features in SNAF to other published splicing neoantigen workflows.
| SNAF | IRIS | ASNEO | NeoSplice | |
|---|---|---|---|---|
| Automated Program Features | ||||
| in-silico translation | ||||
| MHC binding predictions | ||||
| Tumor-specific expression | ||||
| Immunogenicity predictions | ||||
| Surface antigen predictions | ||||
| Parallization | ||||
| Interactive web app | ||||
| Interface to proteomics analysis | ||||
| Principal tumor specificy score | ||||
| Custom normal tissue reference | ||||
| Long-read validation | ||||
| Differential gene expression | ||||
| Gene-set enrichment | ||||
| Splicing factor activity prediction | ||||
| Advanced visualization | ||||
| Integrated survival analysis | ||||
| Stand-alone python module |