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. 2024 May 20;44(11):1658–1662. doi: 10.1038/s41372-024-01996-2

Table 2.

Comparison of protocol-mandated cortisol levels (µg/dl) in patients with or without concerns for adrenal insufficiency.

Did patient have the following concerns for AI? Cortisol levels (Median (IQR))
Yes No
1. Signs of AIa that required clinical team intervention

6.5 (3.1, 12.7)

(n = 4)

9.2 (4.8, 15.3)

(n = 67)

2. Clinical team restarted steroids due to signs of AI

8.7 (2.9, 14.4)

(n = 2)

9.0 (4.8, 15.3)

(n = 69)

3. Signs of AI based on either clinical team intervention or restarting steroids

6.5 (2.9, 14.4)

(n = 6)

9.2 (4.8, 15.3)

(n = 65)

Yes No
Failed ACTH stimulation test

10.4 (1.6, 19.2)

(n = 2)

5.0 (2.8, 6.4)

(n = 34)

There were no differences in levels between AI and no AI groups by Wilcoxon rank sum test.

AI adrenal insufficiency, ACTH adrenocorticotropic hormone, IQR interquartile range.

aHypoglycemia, hyponatremia, hypotension.