Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Sep 17;38(11):2443–2455. doi: 10.1038/s41375-024-02411-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — A patient ASC-01, BCR::ABL1 IS level (blue) and E459K-BSNV VAF (purple) over time, starting before (white background), then during treatment with asciminib (pink background), until asciminib cessation, B patient ASC-41, BCR::ABL1 IS level (blue), and G250E- (lavender), Y253H- (black), T315I- (orange), F359I- (green), E459K- (maroon) BSNV VAF over time, before (white background) and during (pink background) asciminib treatment C patient ASC-04, BCR::ABL1 IS level results (blue) and I502F-BSNV VAF (teal) before (white background) and during (pink background) asciminib treatment, D patient ASC-23, BCR::ABL1 IS level (blue) and T315I-BSNV VAF (orange) before (white background) and during (pink background) asciminib treatment. BCR::ABL1 IS level (left y-axis), BSNV expressed as variant allele frequency (right y-axis) over time (months, x-axis), BSNV, BCR::ABL1 single nucleotide variant, VAF, variant allele frequency, BD, bis in die, twice a day, IS, international scale.