TABLE 3.
Distribution of alleles in B. pertussis strains from different countries
| Allelea | % (no. of strains) inb:
|
|||||
|---|---|---|---|---|---|---|
| Finland (n = 20) | Sweden (n = 25) | Germany (n = 17) | The Netherlands (n = 20) | France (n = 20) | Total (n = 102) | |
| ptxC1 | 80 (16) | 68 (17) | 24 (4) | 30 (6) | 25 (5) | 47 |
| ptxC2 | 20 (4) | 32 (8) | 76 (13) | 70 (14) | 75 (15) | 53 |
| ptxA1 | 100 (20) | 100 (25) | 100 (17) | 100 (20) | 100 (20) | 100 |
| prn1 | 5 (1) | 0 (0) | 6 (1) | 0 (0) | 5 (1) | 3 |
| prn2 | 95 (19) | 88 (22) | 76 (13) | 95 (20) | 75 (15) | 87 |
| prn3 | 0 (0) | 12 (3) | 18 (3) | 5 (1) | 20 (4) | 10 |
| tcfA2 | 100 (20) | 88 (22) | 82 (14) | 95 (19) | 80 (16) | 89 |
| tcfA3 | 0 (0) | 12 (3) | 18 (3) | 5 (1) | 20 (4) | 11 |
| St-2 | 90 (18) | 64 (16) | 6 (1) | 15 (3) | 0 (0) | 37 |
| St-3 | 10 (2) | 20 (5) | 94 (16) | 85 (17) | 90 (18) | 57 |
| St-2 + 3 | 0 (0) | 16 (4) | 0 (0) | 0 (0) | 10 (2) | 6 |
a
ptxC, pertussis toxin S3 subunit; ptxA, pertussis toxin S1 subunit; St, serotype.
b
The distributions of the alleles and serotypes were analyzed with the exact test. The frequencies of ptxC and the serotypes were significantly different in the five countries (P ≤ 0.0001). The frequencies of the other alleles did not differ significantly between the countries.