Table 4.
Result of histologic analysis in UC-MSC and secretome groups
| Variable | Overall | p-value | UC-MSC | p-value | Secretome | p-value |
|---|---|---|---|---|---|---|
| (n = 15) | (n = 7) | (n = 8) | ||||
| N (%) | N (%) | N (%) | ||||
| Inflammation (mean) | 1.0 | 1.0 | 1.0 | |||
| Preoperative | ||||||
| Absent | 9 (64.3) | 6 (42.9) | 3 (21.4) | |||
| Focal low | 3 (21.4) | 0 | 3 (21.4) | |||
| Focal Moderate | 0 | 0 | 0 | |||
| Multifocal abundant | 2 (14.3) | 1 (7.1) | 1 (7.1) | |||
| Postoperative | ||||||
| Absent | 5 (50) | 4 (40) | 1 (10) | |||
| Focal low | 3 (30) | 1 (10) | 2 (20) | |||
| Focal moderate | 1 (10) | 1 (10) | 0 | |||
| Multifocal abundant | 1 (10) | 0 | 1 (10) | |||
| Regeneration (mean) | 0.564 | 0.317 | 1.00 | |||
| Preoperative | ||||||
| Absent | 6 (42.9) | 3 (21.4) | 3 (21.4) | |||
| Focal small | 6 (42.9) | 3 (21.4) | 3 (21.4) | |||
| Focal large | 2 (14.3) | 1 (7.1) | 1 (7.1) | |||
| Multifocal | 0 | 0 | 0 | |||
| Postoperative | ||||||
| Absent | 3 (30) | 1 (10) | 2 (20) | |||
| Focal small | 4 (40) | 4 (40) | 0 | |||
| Focal large | 3 (30) | 1 (10) | 2 (20) | |||
| Multifocal | 0 | 0 | ||||
| Fibrosis | 0.48 | 0.414 | 1.00 | |||
| Preoperative | ||||||
| Absent | 0 | 0 | 0 | |||
| Proliferation of perimysial connective tissue only | 1 (7.1) | 0 | 1 (7.1) | |||
| Additional mild endomysial fibrosis | 2 (14.3) | 0 | 2 (14.3) | |||
| Additional moderate endomysial fibrosis | 3 (7.1) | 2 (14.3) | 1 (7.1) | |||
| Additional severe endomysial fibrosis | 8 (57.1) | 5 (35.7) | 3 (21.4) | |||
| Postoperative | ||||||
| Absent | ||||||
| Proliferation of perimysial connective tissue only | 1 (10) | 0 | 1 (10) | |||
| Additional mild endomysial fibrosis | 1 (10) | 1 (10) | 0 | |||
| Additional moderate endomysial fibrosis | 4 (40) | 2 (20) | 2 (20) | |||
| Additional severe endomysial fibrosis | 4 (40) | 3 (30) | 1 (10) |