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. 2024 Oct 28;8(1):e202402808. doi: 10.26508/lsa.202402808

Figure 1. Differentially expressed genes in RA versus OA FLS.

Figure 1.

(A) Volcano plot of the computed log2 fold change and P-values for all the expressed genes in RA versus OA fibroblast-like synoviocytes (t test), where the six genes with the highest P-values were marked. Genes were labeled as down-regulated in RA, up-regulated in RA, or non-significant (NS). (B) Most enriched pathways of the differentially expressed genes in RA versus OA fibroblast-like synoviocytes (1,093 genes with tdiff-expr > 2), combined from GO (28), KEGG (29), and Reactome (30), ranked by adjusted P-values.