TABLE 1.
Removal of OspC antibodies from early Lyme disease sera by adsorption with OspC-Dra, C16, or C7
| Serum sample | OspC ELISA reactivitya after adsorption with:
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Untreated serum
|
OspC
|
OspC-Dra
|
C16
|
C7
|
||||||
| IgM | IgG | IgM | IgG | IgM | IgG | IgM | IgG | IgM | IgG | |
| 1 | 40,960 | 20,480 | ND | ND | 160 | 640 | 640 | 320 | 640 | 640 |
| 2 | 81,920 | 2,560 | ND | ND | ND | 160 | 160 | 160 | ND | 320 |
| 3 | 20,480 | 640 | ND | ND | ND | 80 | 160 | 160 | 80 | 80 |
| 4 | 40,960 | 10,240 | ND | ND | 2,560 | 320 | 2,560 | 320 | 2,560 | 640 |
| 5 | 5,120 | 320 | ND | ND | 160 | ND | 160 | ND | 320 | ND |
a
Reciprocal of last dilution with adsorbance value of ≥0.200 above that of normal serum control. ND, no ELISA reactivity detected.