Table 3.
Analysis of laboratory tests by different Pittsburgh sleep quality index scores groups.
| Parameters | PSQI scores groups* | P | |||
|---|---|---|---|---|---|
| Severe and very severe (n=141) |
Moderate (n=135) |
Mild (n=114) |
Normal (n=19) |
||
| Endocrinological biomarkers | |||||
| T3 | 1.40 (1.24, 1.53) | 1.47 (1.31, 1.61) | 1.50 (1.28, 1.63) | 1.42 (1.28, 1.48) | 0.156 |
| T4 | 113.47 (101.71, 125.69) | 108.75 (99.07, 124.19) | 113.32 (99.51, 125.33) | 108.89 (100.85, 111.90) | 0.289 |
| FT3 | 4.87 (4.63, 5.22) | 4.95 (4.56, 5.27) | 5.01 (4.63, 5.33) | 4.64 (4.39, 4.95) | 0.185 |
| FT4 | 12.25 (11.21, 13.22) | 12.25 (10.84, 13.04) | 12.23 (10.92, 13.15) | 12.14 (10.39, 13.73) | 0.866 |
| TSH | 1.33 (0.96, 1.92) | 1.55 (0.97, 2.10) | 1.61 (1.08, 2.06) | 1.43 (1.31, 2.19) | 0.481 |
| TPOAb | 0.69 (0.30, 1.35) | 0.50 (0.40, 1.19) | 0.60 (0.30, 1.20) | 0.64 (0.40, 1.00) | 0.999 |
| TGAb | 0.10 (0.00, 0.10) | 0.10 (0.00, 0.10) | 0.10 (0.00, 0.20) | 0.10 (0.00, 0.20) | 0.055 |
| GH | 0.36 (0.16, 0.82) | 0.51 (0.23, 1.37) | 0.38 (0.14, 0.89) | 0.26 (0.22, 0.55) | 0.345 |
| FSH | 13.99 (4.56, 52.90) | 11.22 (4.47, 59.05) | 9.81 (5.01, 52.19) | 13.86 (4.10, 57.71) | 1.000 |
| LH | 9.88 (3.55, 21.75) | 12.76 (4.59, 23.92) | 7.23 (4.37, 22.48) | 17.40 (8.05, 31.52) | 0.515 |
| PRL | 347.26 (249.34, 499.08) | 418.43 (273.61, 534.79) | 377.87 (248.83, 519.82) | 351.78 (273.89, 483.44) | 0.691 |
| Tumor biomarkers | |||||
| CA125 | 7.50 (5.00, 10.48) | 8.50 (6.00, 11.30) | 7.25 (5.58, 9.65) | 6.50 (4.90, 9.32) | 0.197 |
| CA199 | 6.30 (3.90, 12.16) | 6.60 (4.00, 8.70) | 7.55 (3.90, 12.17) | 6.70 (4.20, 9.32) | 0.768 |
| AFP | 2.10 (1.60, 2.71) | 2.61 (1.86, 3.08) | 2.20 (1.72, 2.74) | 3.11 (2.30, 3.47) | 0.059 |
| CEA | 1.40 (0.81, 1.80) | 1.10 (0.79, 1.50) | 1.30 (0.85, 1.64) | 1.45 (0.70, 1.78) | 0.626 |
| Immunological biomarkers | |||||
| WBC count, *109/L | 5.40 (4.30, 6.30) | 5.21 (4.19, 6.00) | 5.32 (4.48, 6.08) | 6.30 (4.65, 7.20) | 0.187 |
| hs-CRP, mg/L | 0.50 (0.50, 0.50) | 0.50 (0.50, 0.50) | 0.50 (0.50, 0.50) | 0.50 (0.50, 0.58) | 0.793 |
| SMA, n (%) | |||||
| – | 140 (99.29%) | 134 (99.26%) | 114 (100.00%) | 19 (100.00%) | 1.000 |
| ± | 1 (0.71%) | 1 (0.74%) | 0 (0.00%) | 0 (0.00%) | |
| AMA, n (%) | |||||
| – | 141 (100.00%) | 134 (33.01%) | 114 (100.00%) | 19 (100.00%) | 0.655 |
| + | 0 (0.00%) | 1 (0.74%) | 0 (0.00%) | 0 (0.00%) | |
| ANA, n (%) | |||||
| – | 100 (70.92%) | 103 (76.30%) | 90 (78.95%) | 15 (78.95%) | 0.515 |
| ± | 33 (23.40%) | 22 (16.30%) | 15 (13.16%) | 3 (15.79%) | |
| + | 8 (5.67%) | 10 (7.40%) | 9 (7.89%) | 1 (5.26%) | |
Data are described as median and interquartile, and number and percentage.
AFP, alpha-fetoprotein; AMA, anti-mitochondrial antibody; ANA, anti-nuclear antibody; CA125, cancer antigen 125; CA199, cancer antigen 199; CEA, carcinoembryonic antigen; FSH, follicle stimulating hormone; FT3, free triiodothyronine; FT4, free tetraiodothyronine; GH, growth hormone; hs-CRP, hypersensitive C-reaction protein; LH, luteinizing hormone; PRL, prolactin; PSQI, Pittsburgh sleep quality index; SMA, smooth muscle antibody; T3, triiodothyronine; T4, tetraiodothyronine; TSH, thyroid stimulating hormone; TPOAb, thyroid peroxidase antibody; TGAb, thyroglobulin antibody; WBC white blood cell.
*PSQI scores: 0-5 denoting normal sleep quality; 6-10 suggesting a mild sleep disorder; 11-15 indicating a moderate sleep disturbance; 16-20 reflecting a severe sleep disorder; and 21 representing a very severe sleep disorder.