Table 2.

Independent Predictors of Measures of Autonomic Dysfunction Among Childhood Cancer Survivors

	Adjusted OR (95% CI) for ≥2 Measures of Autonomic Dysfunction	P Value
Age at evaluation	1.03 (1.01-1.05)	<0.001
Smoking history	1.40 (1.02-1.92)	0.039
Chest-directed radiation	2.06 (1.52-2.75)	<0.001
Cranial radiation	1.49 (1.08-2.05)	0.015
Carboplatin	2.50 (1.42-4.40)	0.001

Other variables included in this multivariable model, but not identified as independent predictors, were age at cancer diagnosis, sex, body mass index, alkylating agent, and anthracycline therapy. Note that body mass index was included in the model as a 3-category variable.