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. 2024 Oct 28;23:384. doi: 10.1186/s12933-024-02476-9

Table 2.

Correlation analysis of SHR, ABG and HbA1c with established markers of PAH severity

Variables SHR ABG HbA1c
Coefficient (r) P value Coefficient (r) P value Coefficient (r) P value
WHO-FC 0.196 < 0.001 0.267 < 0.001 0.150 < 0.001
6MWD − 0.187 < 0.001 − 0.287 < 0.001 − 0.212 < 0.001
ln (NT-proBNP) 0.181 < 0.001 0.384 < 0.001 0.339 < 0.001
Pericardial effusion 0.094 0.019 0.220 < 0.001 0.220 < 0.001
RAP 0.067 0.097 0.259 < 0.001 0.259 < 0.001
mPAP 0.022 0.589 0.053 0.188 0.030 0.459
PVR 0.163 < 0.001 0.202 < 0.001 0.205 < 0.001
Cardiac index − 0.085 0.035 − 0.304 < 0.001 − 0.333 < 0.001
SVI − 0.105 0.009 − 0.341 < 0.001 − 0.355 < 0.001
SVO2 − 0.134 0.001 − 0.324 < 0.001 − 0.302 < 0.001

ABG, admission blood glucose; HbA1c, hemoglobin A1c; mPAP, mean pulmonary arterial pressure; ln, logarithmically transformed; NT-proBNP, N-terminal pro-brain natriuretic peptide; PAH, pulmonary arterial hypertension; PVR, pulmonary vascular resistance; RAP, right atrial pressure; 6MWD, 6-min walk distance; SHR, stress hyperglycemia ratio; SVO2, mixed venous oxygen saturation; SVI, stroke volume index; WHO-FC, World Health Organization functional class