Table 1.

Physicochemical Characteristics of HNPs and BHNPs

Formulation Code	Particle Size (nm)	Polydispersity Index (PDI)	ζ-Potential (mV)	Encapsulation Efficiency (%)
HNP-50	92.73 ± 03.97	0.23 ± 0.01	−52.98 ± 1.94	NA
BHNP-50	147.47 ± 1.40	0.16 ± 0.04	−53.87 ± 4.81	89.75 ± 0.02
HNP-100	244.43 ±10.25	0.25 ± 0.03	−50.87 ± 1.40	NA
BHNP-100	218.83 ± 4.53	0.15 ± 0.01	−46.22 ± 2.74	89.76 ± 0.12

Notes: HNPs (human serum albumin nanoparticles), BHNPs (belinostat-HNPs), 50 and 100 indicate 50 and 100 mg HSA. Data represented as mean ± SD (n = 3).

Abbreviation: NA, not applicable.