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. 2013 Sep 2;2013(9):CD009695. doi: 10.1002/14651858.CD009695.pub2

Comparison 5. Subgroup analysis: data publication.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Amphetamine use (UA) 7   Mean Difference (IV, Random, 95% CI) Subtotals only
1.1 Published data 3 138 Mean Difference (IV, Random, 95% CI) ‐0.22 [‐0.83, 0.39]
1.2 Unpublished data 4 335 Mean Difference (IV, Random, 95% CI) ‐0.86 [‐3.21, 1.50]
2 Amphetamine use (hair analysis) 1   Mean Difference (IV, Random, 95% CI) Subtotals only
2.1 Published data 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2.2 Unpublished data 1 22 Mean Difference (IV, Random, 95% CI) 0.53 [‐6.02, 7.08]
3 Sustained abstinence 6   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
3.1 Published data 1 73 Risk Ratio (M‐H, Random, 95% CI) 1.03 [0.49, 2.17]
3.2 Unpublished data 5 486 Risk Ratio (M‐H, Random, 95% CI) 1.13 [0.83, 1.54]
4 Self reported amphetamine use 3   Mean Difference (IV, Random, 95% CI) Subtotals only
4.1 Published data 2 104 Mean Difference (IV, Random, 95% CI) ‐2.25 [‐7.02, 2.51]
4.2 Unpublished data 1 29 Mean Difference (IV, Random, 95% CI) 7.71 [‐5.10, 20.52]
5 Retention in treatment 11 791 Risk Ratio (M‐H, Random, 95% CI) 1.01 [0.90, 1.14]
5.1 Published data 11 791 Risk Ratio (M‐H, Random, 95% CI) 1.01 [0.90, 1.14]
5.2 Unpublished data 0 0 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
6 Amphetamine craving (at the end of study) 2   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
6.1 Published data 0 0 Std. Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6.2 Unpublished data 2 144 Std. Mean Difference (IV, Random, 95% CI) 0.07 [‐0.44, 0.59]
7 Dropouts due to any adverse event 10   Risk Difference (M‐H, Random, 95% CI) Subtotals only
7.1 Published data 5 292 Risk Difference (M‐H, Random, 95% CI) 0.00 [‐0.04, 0.05]
7.2 Unpublished data 5 348 Risk Difference (M‐H, Random, 95% CI) 0.01 [‐0.05, 0.07]
8 Dropouts due to cardiovascular adverse events 8   Risk Difference (M‐H, Random, 95% CI) Subtotals only
8.1 Published data 2 103 Risk Difference (M‐H, Random, 95% CI) 0.02 [‐0.04, 0.09]
8.2 Unpublished data 6 267 Risk Difference (M‐H, Random, 95% CI) ‐0.00 [‐0.04, 0.04]
9 Dropouts due to psychiatric adverse events 7   Risk Difference (M‐H, Random, 95% CI) Subtotals only
9.1 Published data 3 152 Risk Difference (M‐H, Random, 95% CI) ‐0.03 [‐0.08, 0.03]
9.2 Unpublished data 4 138 Risk Difference (M‐H, Random, 95% CI) ‐0.01 [‐0.07, 0.05]