Table 4.

Domains of neuropsychiatric inventory questionnaire severity score at baseline and at 12 weeks after treatment with CBD-rich oil

Domain NPI-Q severity	Median at baseline (IQR)	Median at 12 weeks (IQR)	Median differencea
Delusions	2 (1–3)	1 (0–2)	p <0.001
Hallucinations	2 (1–3)	1 (0–2)	p <0.001
Agitation/aggression	2 (1–3)	1 (0–2)	p <0.001
Depression/dysphoria	2 (1–2)	1 (0–1)	p <0.001
Anxiety	2 (1–3)	1 (0–2)	p <0.001
Elation/euphoria	2 (1–3)	1 (0–2)	p <0.001
Apathy/indifference	2 (1–3)	1 (0–2)	p <0.001
Disinhibition	2 (1–3)	1 (0–2)	p <0.001
Irritability/lability	2 (1–3)	1 (0–2)	p <0.001
Motor disturbance	2 (1–2.5)	1 (0–2)	p <0.001
Nightime behaviors	2 (1–3)	1 (0–2)	p <0.001
Appetite/eating	2 (1–3)	1 (0–2)	p <0.001

CBD, cannabidiol; IQR, interquartile range; NPI-Q, Neuropsychiatric Inventory Questionnaire.

^aWilcoxon test.