TABLE 6.
Summary of the two‐way factorial design results for the effect of the extract and the drug on the growth inhibition halo diameter in different indicators.
| Indicator | Source of changes | Sum of squares | Degrees of freedom | Average of squares | Test statistic (F) | Significant level | Effect size |
|---|---|---|---|---|---|---|---|
| E. coli | Fixed effect | 8742.250 | 1 | 8742.250 | 15,352.244 | .000 | 0.998 |
| Extract effect | 2881.806 | 3 | 960.602 | 1686.911 | .000 | 0.995 | |
| Medicine effect | 222.167 | 2 | 111.083 | 195.073 | .000 | 0.942 | |
| Reaction | 98.611 | 6 | 16.435 | 28.862 | .000 | 0.878 | |
| Error effect | 13.667 | 24 | 0.569 | – | – | – | |
| Total effect | 11,958.500 | 36 | – | – | – | – | |
| S. aureus | Fixed effect | 5220.062 | 1 | 5220.062 | 11,564.446 | .000 | 0.999 |
| Extract effect | 6705.187 | 3 | 2235.062 | 1580.173 | .000 | 0.998 | |
| Medicine effect | 13.542 | 2 | 6.771 | 15.000 | .000 | 0.556 | |
| Reaction | 40.625 | 6 | 6.771 | 15.000 | .000 | 0.789 | |
| Error effect | 10.833 | 24 | 0.451 | – | – | – | |
| Total effect | 11,990.250 | 36 | – | – | – | – | |
| P. aeruginosa | Fixed effect | 10,937.674 | 1 | 10,937.674 | 16,071.684 | .000 | 0.999 |
| Extract effect | 3226.187 | 3 | 1075.396 | 1580.173 | .000 | 0.995 | |
| Medicine effect | 576.514 | 2 | 288.257 | 423.561 | .000 | 0.972 | |
| Reaction | 262.542 | 6 | 43.757 | 64.296 | .000 | 0.944 | |
| Error effect | 16.333 | 24 | 0.681 | – | – | – | |
| Total effect | 15,019.250 | 36 | – | – | – | – | |
| S. mutans | Fixed effect | 6320.250 | 1 | 6320.250 | 6791.910 | .000 | 0.996 |
| Extract effect | 1350.139 | 3 | 450.046 | 483.632 | .000 | 0.984 | |
| Medicine effect | 178.167 | 2 | 89.083 | 95.731 | .000 | 0.889 | |
| Reaction | 120.611 | 6 | 20.102 | 21.602 | .000 | 0.844 | |
| Error effect | 22.333 | 24 | 0.931 | – | – | – | |
| Total effect | 7991.500 | 36 | – | – | – | – | |
| S. enterica | Fixed effect | 8487.016 | 1 | 8487.016 | 11,723.072 | .000 | 0.998 |
| Extract effect | 1314.352 | 3 | 438.117 | 605.169 | .000 | 0.987 | |
| Medicine effect | 36.948 | 2 | 18.474 | 25.518 | .000 | 0.680 | |
| Reaction | 19.122 | 6 | 3.187 | 4.402 | .004 | 0.524 | |
| Error effect | 17.375 | 24 | 0.724 | – | – | – | |
| Total effect | 9874.813 | 36 | – | – | – | – | |
| B. cereus | Fixed effect | 8579.391 | 1 | 8579.391 | 9341.643 | .000 | 0.997 |
| Extract effect | 1101.977 | 3 | 367.326 | 399.962 | .000 | 0.980 | |
| Medicine effect | 38.198 | 2 | 19.099 | 20.796 | .000 | 0.634 | |
| Reaction | 28.705 | 6 | 4.784 | 5.209 | .001 | 0.566 | |
| Error effect | 22.042 | 24 | 0.918 | – | – | – | |
| Total effect | 9770.313 | 36 | – | – | – | – |