Extended Data Fig. 5. EDI048 improves clinical diarrhea symptoms in experimentally challenged calves.
a, EDI048 reduces overall frequency of severe diarrhea and moderate-to-severe diarrhea. There were 7 calves per group, and each square (untreated) and circle (EDI048 treated) represents frequency of diarrhea for an individual calf over 7 days. p values were determined using unpaired, two-tailed t test. Data shown as a ‘box and whiskers’ plot; the box extends from the 25th to 75th percentiles, and whiskers with minimum to maximum showing all data points, and the center is median. b. Microbiological and clinical end-points measured 7 days post-cessation of drug treatment, details as described in Fig. 3b,c.