Table 1.

Sociodemographic and clinical data of IBD patients from a prospective population-based registry in Northern France from 1988 to 2017 (n = 22,879).

Characteristics at diagnosis	All patients	Males	Females	p-value
	(n = 22,879)	(n = 10,925)	(n = 11,954)
Disease type
CD	13,445 (58.8%)	5910 (54.0%)	7535 (63.0%)	<0.0001
UC	8803 (38.5%)	4699 (43.0%)	4104 (34.3%)
IBDU	631 (2.8%)	316 (3.0%)	315 (2.6%)
CD
Median [IQR] age, years	26 [20–38]	26 [19–39]	26 [20–38]	0.128
Female gender	7535 (56.0%)
Family history of IBD	1700 (12.6%)	720 (12.2%)	980 (13.0%)	0.154
Median [IQR] time between symptoms onset and diagnosis, months	3 [1; 9]	3 [1; 8]	3 [1; 9]	0.001
Disease sitea
L1	2666 (20.4%)	1176 (20.6%)	1490 (20.3%)	0.476
L2	3913 (30.0%)	1681 (29.4%)	2232 (30.4%)
L3	6467 (49.6%)	2853 (50.0%)	3614 (49.3%)
L4	2951 (21.9%)	1418 (24.0%)	1533 (20.3%)	<0.0001
Behaviora,b
B1	3840 (73.8%)	1443 (73.7%)	1769 (74.9%)	0.550
B2	928 (17.8%)	357 (18.2%)	420 (17.8%)
B3	433 (8.3%)	158 (8.1%)	172 (7.3%)
Perianal disease	658 (4.9%)	374 (6.3%)	284 (3.8%)	<0.0001
Extra-intestinal manifestations	1565 (11.6%)	647 (10.9%)	918 (12.2%)	0.027
UC
Median [IQR] age, years	35 [25–48]	38 [27–51]	32 [24–44]	<0.0001
Female gender	4104 (46.6%)
IBD family history	594 (6.7%)	264 (5.6%)	330 (8.0%)	<0.0001
Median [IQR] time between symptoms onset and diagnosis, months	2 [1; 6]	2 [1; 6]	2 [1; 6]	0.013
Disease sitea
E1	3157 (36.3%)	1536 (33.1%)	1621 (40.0%)	<0.0001
E2	3210 (36.9%)	1802 (38.8%)	1408 (34.7%)
E3	2329 (26.8%)	1304 (28.1%)	1025 (25.3%)
Extra-intestinal manifestations	299 (3.4%)	138 (2.9%)	161 (3.9%)	0.011

^aAccording to the Montreal classification.

^bRecorded in the EPIMAD registry since 2008.