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. 2024 Oct 29;14:25933. doi: 10.1038/s41598-024-77140-z

Table 5.

Outcomes after SRS per patient and CCM.

Outcomes per 181 CCM
Adverse radiation effect 9 (5.0%)
New hemorrhage after SRS
 1 18 (9.9%)
 2 1 (0.6%)
CCM volume at last FU
 Decreased 77 (43.0%)
 Stable 99 (55.3%)
 Increased 3 (1.7%)
 Unknown 2
Zabramski post SRS
 1 15 (10.2%)
 2 87 (59.2%)
 3 34 (23.1%)
 4 11 (7.5%)
 Unknown 34
Zabramski evolution before and after SRS
 Unchanged 100 (68.5%)
 PreSRS = 1 to post SRS 2 12 (8.2%)
 PreSRS = 1 to post SRS 4 5 (3.4%)
 PreSRS = 1 to post SRS 1 5 (3.4%)
 PreSRS = 2 to post SRS 1 18 (12.3%)
 PreSRS = 2 to post SRS 4 4 (2.7%)
 PreSRS = 3 to post SRS 2 1 (0.6%)
 PreSRS = 4 to post SRS 1 1 (0.6%)
 Unknown 35
Outcomes for 170 patients
 Symptom evolution among patient
  Neurologic improvement 69 (42.3%)
  Neurologic stability 81 (49.7%)
  Neurological worsening 13 (8.0%)
  Missing data 7
  New neurological deficit after SRS* 27 (15.9%)
  Transient 15 (8.8%)
  Permanent 12 (7.1%)
  Deficit due to ARE 2 (2.1%)
  Deficit due to a new hemorrhage of treated CCM 11 (6.5%)
  Deficit due to hemorrhage and ARE 2 (2.1%)
  New neurological deficit from other reason 12
  Death

*Headaches and seizures were not taken into account for this classification.

ARE: Adverse radiation effect, CCM: cerebral cavernous malformations, FU: Follow-up, SRS: Stereotactic radiosurgery.