Table II.
Association between the risk of AAV and single nucleotide polymorphism rs2241880.
| Model | Genetype/Allele | Control (%) | AAV (%) | OR (95% CI) | P-value |
|---|---|---|---|---|---|
| Allele | G | 98 (31.8) | 88 (28.6) | Reference | 0.38 |
| A | 210 (68.2) | 220 (71.4) | 1.17 (0.83-1.65) | ||
| Codominant | AA | 71 (46.1) | 78 (50.6) | Reference | 0.68 |
| AG | 68 (44.2) | 64 (41.6) | 0.86 (0.54-1.37) | ||
| GG | 15 (9.7) | 12 (7.8) | 0.73 (0.32-1.66) | ||
| Dominant | AA | 71 (46.1) | 78 (50.6) | Reference | 0.42 |
| AG-GG | 83 (53.9) | 76 (49.4) | 0.83 (0.53-1.30) | ||
| Recessive | AA-AG | 139 (90.3) | 142 (92.2) | Reference | 0.55 |
| GG | 15 (9.7) | 12 (7.8) | 0.78 (0.35-1.73) | ||
| Overdominant | AA-GG | 86 (55.8) | 90 (58.4) | Reference | 0.65 |
| AG | 68 (44.2%) | 64 (41.6%) | 0.90 (0.57-1.41) |
AAV, antineutrophil cytoplasmic autoantibody-associated vasculitis.