Table III.
Association between risk of AAV and single nucleotide polymorphism rs4663421 in different genotypic models.
| Model | Genetype/Allele | Control (%) | AAV (%) | OR (95% CI) | P-value |
|---|---|---|---|---|---|
| Allele | G | 279 (90.6) | 282 (91.6) | Reference | 0.67 |
| C | 29 (9.4) | 26 (8.4) | 0.89 (0.51-1.55) | ||
| Codominant | GG | 125 (81.2) | 129 (83.8) | Reference | 0.38 |
| GC | 29 (18.8) | 24 (15.6) | 0.80 (0.44-1.45) | ||
| CC | 0 (0.0) | 1 (0.6) | NA (0.00-NA) | ||
| Dominant | GG | 125 (81.2) | 129 (83.8) | Reference | 0.55 |
| GC-CC | 29 (18.8) | 25 (16.2) | 0.84 (0.46-1.51) | ||
| Recessive | GG-GC | 154(100) | 153 (99.3) | Reference | 0.24 |
| CC | 0 (0) | 1 (0.6) | NA (0.00-NA) | ||
| Overdominant | GG-CC | 125 (81.2) | 130 (84.4) | Reference | 0.45 |
| GC | 29 (18.8) | 24 (15.6) | 0.80 (0.44-1.44) |
AAV, antineutrophil cytoplasmic autoantibody-associated vasculitis; NA, not applicable.