Table V.

Genotypes and renal pathology at two single nucleotide polymorphisms of autophagy-related protein 16-like 1 gene.

	rs2241880			rs4663421
Variable	AA + AG (n=61)	GG (n=7)	P-value	CC + CG (n=10)	GG (n=58)	P-value
Berden classificatio, n (%)			0.302			0.268
Focal	32 (52.46)	3 (42.86)		5 (50.00)	30 (51.72)
Sclerotic	16 (26.23)	4 (57.14)		5 (50.00)	15 (25.86)
Crescent	5 (8.20)	0 (0.00)		0 (0.00)	5 (8.62)
Mixed	8 (13.11)	0 (0.00)		0 (0.00)	8 (13.79)
Median normal glomeruli (IQR)	52.63 (18.34,81.67)	20.00 (0.00,81.25)	0.210	43.18 (14.58,66.67)	51.32 (15.63,81.77)	0.801
Sclerotic glomeruli, n (%)	47 (77.05)	7 (100.00)	0.330	9 (90.00)	45 (77.59)	0.370
Degree of disease, % (median, IQR)	21.43 (4.12,52.28)	62.50 (18.75,80.00)	0.042	55.00 (19.41,65.42)	18.47 (4.56,51.14)	0.082
Global sclerosis, n (%)	46 (75.41)	7 (100.00)	0.334	9 (90.00)	44 (75.86)	0.319
Degree of disease, % (median, IQR)	17.43 (3.67,36.20)	37.50 (18.75,75.00)	0.040	31.19 (12.39,46.59)	18.18 (4.12,36.93)	0.185
Segmental sclerosis, n (%)	22 (36.07)	3 (42.86)	0.724	8 (80.00)	17 (29.31)	0.002
Degree of disease, % (median, IQR)	0.00 (0.00,7.14)	0.00 (0.00,25.00)	0.496	10.72 (5.00,22.50)	0.00 (0.00,5.61)	0.002
Crescents, n (%)	37 (60.66)	2 (28.57)	0.104	5 (50.00)	34 (58.62)	0.611
Degree of disease, % (median, IQR)	15.38 (0.00,27.62)	0.00 (0.00,25.00)	0.204	3.34 (0.00,21.63)	13.25 (0.00,29.41)	0.260
Cellular crescents, n (%)	12 (19.67)	0 (0.00)	0.196	2 (20.00)	10 (17.24)	0.833
Mean degree of disease	2.20±5.51	0.00±0.00	0.202	1.38±2.91	2.08±5.58	0.865
Cellular fibrous crescents, n (%)	24 (39.34)	2 (28.57)	0.579	2 (20.00)	24 (41.38)	0.199
Degree of disease, % (median, IQR)	0.00 (0.00,17.92)	0.00 (0.00,15.00)	0.541	0.00 (0.00,3.57)	0.00 (0.00,18.64)	0.166
Fibrous crescents, n (%)	18 (29.51)	2 (28.57)	0.959	3 (30.00)	17 (29.31)	0.965
Degree of disease, % (median, IQR)	0.00 (0.00,15.00)	0.00 (0.00,10.00)	0.880	0.00 (0.00,10.00)	0.00 (0.00,5.73)	0.914