Table 4.

Cox regression analysis with leukopenia as dependent variable.

Variable	HR (95% CI)	p-Value
PEG-IFN-β-1a (vs sc. IFN-β-1a)	0.256 (0.096–0.681)	0.006
Treatment duration (months)	0.993 (0.964–1.022)	0.619
Age at Tx-start (years)	0.998 (0.961–1.037)	0.934
Number of previous therapies	0.649 (0.300–1.403)	0.272
Leukocytes baseline (leukocytes/nl)	0.580 (0.428–0.784)	<0.001

Significant p values are highlighted in bold.

CI, confidence interval; HR, hazard ratio; IFN-β, interferon-beta; Tx, drug treatment.