Table I.
Baseline patient characteristics stratified by clinical improvement based on venous clinical severity score (VCSS)
| Characteristic | Clinical improvement (n = 2187; 83.9%) | LCI (n = 420; 16.1%) | P value |
|---|---|---|---|
| Age, years | 56 (45-66) | 58 (47-67) | .043 |
| Female sex | 1480 (68) | 286 (68) | .9 |
| Race | .001 | ||
| White | 1720 (79) | 345 (82) | |
| African American | 76 (3.5) | 25 (6.0) | |
| Other | 391 (18) | 50 (12) | |
| Ethnicity (Latino) | 115 (5.3) | 19 (4.5) | .5 |
| BMI | .004 | ||
| Underweight (<18.5 kg/m2) | 18 (0.8) | 4 (1.0) | |
| Normal (18.5-24.9 kg/m2) | 538 (25) | 87 (21) | |
| Overweight (25-30 kg/m2) | 716 (33) | 114 (27) | |
| Obese (>30 kg/m2) | 912 (42) | 215 (51) | |
| Anticoagulation | 217 (9.9) | 51 (12) | .2 |
| Prior phlebitis | 250 (11) | 41 (9.8) | .3 |
| Prior DVT | 123 (5.6) | 26 (6.2) | 0.6 |
| Prior PE | 19 (2.7) | 1 (0.9) | .5 |
| Compression therapy before intervention | < .001 | ||
| Daily | 765 (35) | 84 (20) | |
| Most days | 614 (28) | 111 (26) | |
| Intermittent | 509 (23) | 99 (24) | |
| None | 299 (14) | 126 (30) | |
| CEAP classification | .005 | ||
| C4 | 450 (21) | 85 (20) | |
| C3 | 1127 (52) | 186 (44) | |
| C2 | 610 (28) | 149 (35) | |
| Symptoms | |||
| Pain | 2137 (98) | 383 (91) | < .001 |
| Varicosities | 2128 (97) | 388 (92) | < .001 |
| Edema | 1529 (70) | 252 (60) | < .001 |
| Pigmentation | 385 (18) | 71 (17) | .7 |
| Inflammation | 368 (17) | 58 (14) | .13 |
| Induration | 214 (9.8) | 26 (6.2) | .02 |
| Quality of life | |||
| Heaviness | 1479 (70) | 294 (73) | .2 |
| Achiness | 1892 (89) | 349 (86) | .13 |
| Swelling | 1744 (82) | 329 (81) | .7 |
| Throbbing | 1151 (54) | 262 (65) | < .001 |
| Itching | 919 (43) | 203 (50) | .01 |
| Appearance | 1972 (93) | 371 (92) | .5 |
| Impact on work | 1808 (85) | 339 (83) | .5 |
| Any symptom | 2116 (97) | 401 (95) | .2 |
| VCSS before treatment | 7 (6-9) | 6 (4-7) | < .001 |
BMI, Body mass index; CEAP, Clinical-Etiological-Anatomical-Pathophysiological; DVT, deep vein thrombosis; LCI, lack of clinical improvement; PE, pulmonary embolism.
Data presented as median (interquartile range) or number (%).
Boldface P values represent statistical significance (P < .05).