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. 2023 Nov 24;12(2):101726. doi: 10.1016/j.jvsv.2023.101726

Table III.

The pooled event rate per 100 patient-years of venous thromboembolism (VTE) and bleeding according to the duration of anticoagulation treatment

Duration of anticoagulation VTE SVT progression or recurrence DVT PE Major bleeding CRNM and minor bleeding
All studies 27.8 (21.4-34.9) 23.3 (15.8-35.8) 7.9 (5.4-10.9) 1.3 (0.8-2.0) 0.3 (0.2-0.6)a 7.4 (4.0-11.7)
0 days 28.8 (12.0-52.4) 61.5 (11.5-147.6) 8.3 (2.4-17.5) 1.9 (0.8-3.7)a 0.5 (0.1-1.4)a 4.8 (2.8-7.4)a
≤14 days 59.7 (37.7-86.4) 41.3 (17.9-73.9) 13.7 (9.6-18.4)a 3.1 (1.4-5.6)a 0.5 (0.0-2.7)a 1.4 (0.1-4.3)a
15-30 days 25.4 (16.3-36.6) 18.8 (9.7-30.9) 5.5 (2.8-9.1) 0.9 (0.5-1.3)a 0.3 (0.1-0.6)a 5.8 (1.6-12.6)
31-45 days 16.2 (10.4-23.3) 8.2 (3.1-15.8) 7.8 (3.0-14.9) 1.4 (0.2-3.8) 0.3 (0.1-0.7)a 14.2 (5.5-26.8)

CRNM, Clinically relevant non-major; DVT, deep vein thrombosis; PE, pulmonary embolism; SVT, superficial vein thrombosis.

a

Indicates low heterogeneity (P > .05 and I2< 50%).