Resource	Unit Cost	Reference	Assumption
Hospital-based resources
Hospital admission	£ 447.00	PSSRU (2020) section 7.1, NHS reference costs for hospital services, p87.	Patients receive palliative care and chemotherapy side-effect treatments
Non-elective attendance to A&E or similar	£ 382.00	National schedule of NHS cost 2018/2019, code SB97Z, tab: non-elective short stay (NES).	A&E attendances are be related to chemotherapy or procedure complications or due to poorly controlled symptoms attributed to cancer progression. Co-incidental illnesses rarely led to admission in patients with pancreatic cancer, hence are not considered in the costings [53, 54].
Delivery of parenteral chemotherapy at first attendance	£ 307.58	National schedule of NHS cost 2018/2019, code SB13Z.	Costs reflect delivery of complex chemotherapeutic schemes, such as FOLFIRINOX, but not single agent chemotherapy such as gemcitabine or capecitabine. Costs adjusted for inflation.
Delivery of subsequent elements of a chemotherapy cycle	£ 332.83	National schedule of NHS cost 2018/2019, code SB15Z.	Costs reflect delivery of complex chemotherapeutic schemes, such as FOLFIRINOX, but not single agent chemotherapy such as gemcitabine or capecitabine. Costs adjusted for inflation.
Radiotherapy	£ 142.88	National schedule of NHS cost 2018/2019, code 800, tab: total outpatient attendance.	No assumptions made. Costs adjusted for inflation.
Consultant: medical	£ 59.50	PSSRU (2020) section 14, hospital-based doctors, p159.	Consultant cost per working hour £119. Appointment length 30 mins (incorporating administrative tasks).
Dietician appointment	£ 25.00	PSSRU (2020) section 12, hospital-based scientific and professional staff, p151	NHS band 6 dietician, with cost per working hour 50. Appointment length 30 mins (incorporating administrative tasks)
Occupational health appointment	£ 25.00	PSSRU (2020) section 12, hospital-based scientific and professional staff, p151	NHS band 6 occupational therapist, with cost per working hour 50. Appointment length 30 mins (incorporating administrative tasks)
Specialist nurse appointments	£ 25.00	PSSRU (2020) section 12, hospital-based nurses, p155.	NHS band 6 nurse, with cost per working hour £50. Appointment length 30 mins (incorporating administrative tasks)
Community-based resources
GP surgery consultations	£ 39.23	PSSRU (2020) section 10.3b, community-based health care staff-general practitioner, p126.	This unit cost is calculated based on the average duration of GP contact per patient, lasting 9.22 minutes.
GP telephone call	£ 8.41	PSSRU (2020) section 10.4, the cost of online consultations, p128.	This unit cost represents telephone contacts for following up tests or treatments that were decided during a GP surgery consultation.
Primary care nurse appointment	£ 24.50	PSSRU (2020) section 10.1, the cost of online consultations-nurses, p123.	NHS band 6 nurse, with cost per working hour 49. Appointment length 30 mins (incorporating administrative tasks)
Primary care nurse home visits	£ 23.00	PSSRU (2020) section 10.2, GP practice nurse, p124.	NHS band 6 primary care nurse, with cost per working hour 42 plus an average of 10 miles stuff travel per visit. Appointment length 30 mins (incorporating administrative tasks)
Community equipment (stairlift)	£ 654.00	PSSRU (2020) section 7.3, equipment and adaptations, p90.	No assumptions made.
Medical prescriptions
Medical prescriptions		British National Formulary, URL: https://bnf.nice.org.uk/drug/, accessed on: 05/08/2021.	Costs were estimated based on the medication use the patients recorded on their self-completed questionnaires.
“Out of pocket” expenses
Travel for medical appointments (in miles)	£ 0.15	AA motor insurance company, mileage calculator, URL: https://www.theaa.com/driving/mileage-calculator.jsp, accessed on: 30/07/21	Approximate fuel cost £1.40 per litre and engine performance rate of 40 miles per gallon.
Car parking expenditure	n/a	Costs directly reported by patients on self-completed medical resource questionnaire	No assumptions made.