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. 2024 Apr 26;2:37. doi: 10.1038/s44276-024-00056-8

Table 2.

Correlation of T cell and macrophage subtypes with tumor characteristics and status of preoperative chemotherapy.

Cell phenotype, Median (range) n/mm2 CLM size P Preoperative chemotherapy P Primary location P Node positive tumor P
≤3 cm 3 cm Yes No Right Left Yes No
Total CD68+ 48 (2–237) 44 (12–276) 0.83 37 (2–181) 63 (14–273) 0.002 63 (11–273) 40 (2–236) 0.07 43 (2–273) 48 (7–236) 0.33
CD68+CD163+ (M2) 0 (0–36) 2 (0–97) 0.01a 2 (0–97) 0 (0–36) 0.03 1 (0–97) 1 (0–23) 0.72 1 (0–97) 1 (0–36) 0.94
CD68+TGFβ+ 1 (0–29) 1 (0–17) 0.57 1 (0–21) 2 (0–29) 0.02 3 (0–29) 1 (0–21) 0.04 1 (0–29) 1 (0–17) 0.73
CD3+FOXP3+ 0 (0–16) 1 (0–3) 0.97 0 (0–2) 1 (0–16) 0.001 1 (0–2) 0 (0–16) 0.24 0 (0–16) 1 (0–3) 0.08
CD3+CD4+ 3 (0–259) 2 (0–58) 0.66 2 (0–259) 3 (0–145) 0.49 1 (0–58) 4 (0–259) 0.02 3 (0–259) 2 (0–259) 0.88
CD3+CD8+ 1 (0–49) 1 (0–26) 0.97 1 (0–49 1 (0–49) 0.17 1 (0–28) 2 (0–49) 0.03 1 (0–5) 1 (0–49) 0.69
CD3+CD8+pSMADd3+ 0 (0–1) 0 (0–2) 0.47 0 (0–2) 0 (0–10) 0.15 0 (0–2) 0 (0–10) 0.44 0 (0–10) 0 (0–5) 0.02
CD3+CD4+pSMADd3+ 0 (0–3) 0 (0–3) 0.41 0 (0–1) 0 (0–5) 0.002 0 (0–2) 0 (0–5) 0.45 0 (0–5) 0 (0–2) 0.16

Statistically significant p-values are in bold.