Table 2.

Correlation of T cell and macrophage subtypes with tumor characteristics and status of preoperative chemotherapy.

Cell phenotype, Median (range) n/mm2	CLM size		P	Preoperative chemotherapy		P	Primary location		P	Node positive tumor		P
	≤3 cm	3 cm		Yes	No		Right	Left		Yes	No
Total CD68+	48 (2–237)	44 (12–276)	0.83	37 (2–181)	63 (14–273)	0.002	63 (11–273)	40 (2–236)	0.07	43 (2–273)	48 (7–236)	0.33
CD68+CD163+ (M2)	0 (0–36)	2 (0–97)	0.01a	2 (0–97)	0 (0–36)	0.03	1 (0–97)	1 (0–23)	0.72	1 (0–97)	1 (0–36)	0.94
CD68+TGFβ+	1 (0–29)	1 (0–17)	0.57	1 (0–21)	2 (0–29)	0.02	3 (0–29)	1 (0–21)	0.04	1 (0–29)	1 (0–17)	0.73
CD3+FOXP3+	0 (0–16)	1 (0–3)	0.97	0 (0–2)	1 (0–16)	0.001	1 (0–2)	0 (0–16)	0.24	0 (0–16)	1 (0–3)	0.08
CD3+CD4+	3 (0–259)	2 (0–58)	0.66	2 (0–259)	3 (0–145)	0.49	1 (0–58)	4 (0–259)	0.02	3 (0–259)	2 (0–259)	0.88
CD3+CD8+	1 (0–49)	1 (0–26)	0.97	1 (0–49	1 (0–49)	0.17	1 (0–28)	2 (0–49)	0.03	1 (0–5)	1 (0–49)	0.69
CD3+CD8+pSMADd3+	0 (0–1)	0 (0–2)	0.47	0 (0–2)	0 (0–10)	0.15	0 (0–2)	0 (0–10)	0.44	0 (0–10)	0 (0–5)	0.02
CD3+CD4+pSMADd3+	0 (0–3)	0 (0–3)	0.41	0 (0–1)	0 (0–5)	0.002	0 (0–2)	0 (0–5)	0.45	0 (0–5)	0 (0–2)	0.16

Statistically significant p-values are in bold.