Table 3.
Year | Sample | Assay | Viral target type | Outcome | Reference |
---|---|---|---|---|---|
2014 | 52 FFPE tumour tissue | nPCR, chromogenic in situ hybridisation and IHC | DNA (L1 gene), Protein (L1 protein) |
12 samples were positive for HPV, with 9 positive for HPV-6 and 3 positive for HPV-16. All HPV positive samples were positive for L1 protein |
Vidone et al. [207] |
2015 | 31 FFPE and 8 frozen GB tumours | qPCR, IHC | DNA (HPV16, E6 gene; HPV18, L1 gene), Protein (HPV L1 protein) |
8/39 GB tumours were positive for HPV DNA, out of which 6 were positive for HPV-16 and 2 were positive for HPV-18 Only 3 HPV positive samples were used in IHC and they are all positive for L1 protein |
Hashida et al. [156] |