Table 1.
Cytology and mutation data of the 195 LBC samples.
| Category of diagnosis | Histological classification (number of cases) | Cytology | Genetic analysis | ||
|---|---|---|---|---|---|
| Malignant or suspicious | Negative | Driver mutation (+) | Driver mutation (−) | ||
| Primary endometrial malignancy (n = 39) | Endometrial carcinoma | ||||
| Endometrioid carcinoma (33) | 20 | 13 | 25 | 8 | |
| Carcinosarcoma (2) | 2 | 0 | 2 | 0 | |
| Clear cell carcinoma (2) | 1 | 1 | 1 | 1 | |
| Mucinous carcinoma (1) | 1 | 0 | 1 | 0 | |
| Endometrial sarcoma | |||||
| Low-grade endometrial stromal sarcoma (1) | 0 | 1 | 0 | 1 | |
| Non-endometrial malignancy (n = 15) | Cervical cancer (8) | 6 | 2 | 5 | 3 |
| Ovarian cancer (6) | 2 | 4 | 1 | 5 | |
| Metastatic cancer (1) | 1 | 0 | 1 | 0 | |
| Premalignant disease (n = 16) | Endometrial hyperplasia (9) | 0 | 9 | 6 | 3 |
| Endometrial polyp(s) (7) | 0 | 7 | 2 | 5 | |
| Benign/no disease (n = 125) | Myoma uteri/adenomyosis (66) | 0 | 66 | 17 | 49 |
| CIN (11) | 0 | 11 | 4 | 7 | |
| Benign ovarian tumour (13) | 0 | 13 | 3 | 10 | |
| No disease (35) | 0 | 35 | 8 | 27 | |
| Total (n = 195) | 33 | 162 | 76 | 119 | |