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. 2024 Oct 30;19(10):e0305697. doi: 10.1371/journal.pone.0305697

Table 2. Data of different outcomes are reported as median and 95% CI for LOAD, posture, mobility, pain and ROM and mean and 95% CI for GLS, AC and Von Frey grams, at baseline and during different groups and times of administration.

Baseline UCII®-BW
(4week)
UCII®-BW
(8week)
Washout Placebo
(4weeks)
Placebo
(8week)
Owner assessment
Load 17 (12–21) 11 (8–17) 13 (8–15) 14 (10–19) 15 (9–19) 15 (8–21)
Veterinarian assessment
Posture 2 (2–2) 2 (2–2) 2 (2–2) 2 (1.26–2 2 (2–2) 2 (2–2)
Mobility 2 (2–3) 2 (2–2.5) 2 (2–2) 2 (2–2.5) 2 (2–2.5) 2 (2–2.5)
Pain 2 (2–3) 2 (2–3) 2 (2–2.4) 3 (3–1) 2 (1.75–3) 3 (2–3.4)
ROM 3 (2–3) 2 (2–3) 2 (2–3) 2 (2–3) 3 (2–3) 3 (2–3)
Instrumental assessment
GLS 93
(90–97)
96
(92–105)
99
(89–102)
92
(87–101)
95
(89–101)
98
(90–102)
AC
Q1
Q2
Q3

6120 (4900–7340)
6178
(5022–7333)
6185
(4898–7472)

6645
(4410–8880)
6975
(4603–9347)
6916
(4677–9155)

5963
(3426–8500)
6077
(3460–8696)
5991
(3413–8569)

7477
(4657–10297)
7570
(4880–10260)
7570
(4870–10268)

7657
(2486–12829)
7740
(2685–12794)
7766
(2746–12786)

7058
(2972–11143)
7117
(3132–11102)
7193
(3275–11112)
Von Frey
(g)
355
(275–436)
317
(234–400)
393
(293–493)
311
(251–372)
212
(153–271)
327
(227–428)

No differences were found between times and groups of supplementations (p = 0.38).