Table 3.
Odds ratios and CI for the risk of residual melanoma at WLE
Univariate model | Multivariate model | |||
---|---|---|---|---|
OR | 95% CI | OR | 95% CI | |
Time from diagnosis to wide local excision (+1 day) | 1 | 1–1 | ||
Sex (male vs. female) | 0.98 | 0.42–2.28 | 0.14 | 0.02–0.85 |
Age at diagnosis (+1 year) | 1.06 | 1.02–1.1 | 1.02 | 0.96–1.09 |
Type of melanoma | ||||
In situ vs. surface diffusion | 6.7 | 1.2–37.6 | ||
In situ vs. epithelioid | 0.47 | 0.12–1.78 | ||
In situ vs. nodular | 0.92 | 0.26–3.18 | ||
In situ vs. lentigo maligna | 0.69 | 0.41–3.31 | ||
Superficial spreading vs. epithelioid | 0.07 | 0.01–0.36 | ||
Superficial spreading vs. nodular | 0.14 | 0.28–0.66 | ||
Superficial spreading vs. lentigo maligna | 0.1 | 0.02–0.65 | ||
Epithelioid vs. nodular | 1.95 | 0.64–6 | ||
Epithelioid vs. lentigo maligna | 1.47 | 0.34–6.41 | ||
Nodular vs. lentigo maligna | 0.75 | 0.19–3.03 | ||
WLE length (+1 cm) | 1.04 | 0.85–1.27 | ||
WLE width (+1 cm) | 1.5 | 1.02–2.2 | ||
WLE thickness (+1 cm) | 2.01 | 1.11–3.65 | ||
Breslow thickness (+1 mm) | 1.36 | 1.15–1.61 | 1.41 | 1.06–1.88 |
Intratumoral infiltrate (Yes vs. No) | 0.92 | 0.23–3.67 | ||
Peritumoral infiltrate (Yes vs. No) | 0.39 | 0.1–1.56 | ||
Ulcerations (Yes vs. No) | 18.86 | 2.35–151.7 | ||
Site of melanoma | ||||
Head-neck vs. limbs | 4.2 | 1.41–12.47 | ||
Head-neck vs. torso | 8.17 | 2.57–25.94 | ||
Head-neck vs. other | 4.67 | 0.53–40.89 | ||
Limbs vs. torso | 1.94 | 0.66–5.72 | ||
Limbs vs. other | 1.11 | 0.13–9.36 | ||
Torso vs. other | 0.57 | 0.06–4.98 |
CI, confidence interval; OR, odds ratio; WLE, wide local excision.