Figure 2.

IL-33 increased BMSCs' ability to migrate to the damaged liver through the CCR2/CCL2 axis. (A) Comparison of chemokine ligands in ALF rats' liver. (B) Protein levels of CCL2 in the liver of normal rats and those with ALF. (C, D) The knockdown efficiency of CCR2 in BMSCs was determined. (E) A transwell assay was performed to determine the migration ability of BMSCs to CCL2 in each group. (F) In vivo imaging was performed to observe the homing of BMSCs in rats with ALF. n = 3 per group. ⁣^∗p < 0.05, ⁣^∗∗p < 0.01, and ⁣^∗∗∗∗p < 0.0001.