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. 2024 Oct 17;15:1463474. doi: 10.3389/fgene.2024.1463474

TABLE 2.

A summary of targeted and non-targeted functional DNA markers, their targets and used PCR strategies.

Marker Target PCR strategy Detection
SCOT Start codon Single primer-based amplification assay targeting the start codon AGE
CDDP Conserved DNA regions of specific genes Single primer-based amplification assay targets conserved DNA priming sites with differential distribution across the genome AGE
SRAP Open Reading frame It uses two primers with a distinct primer structure, a random filler sequence, an AT OR GC-rich core, and 3 selective nucleotides at the 3′end to enable the amplification of various regions of the genome PAGE
TRAP EST It amplifies various genome regions using an arbitrary SRAP primer and an EST sequence-derived primer PAGE
CoRAP Conserved intron/EST It uses two primers: a fixed primer from EST sequences, an arbitrary primer with a core sequence ‘CACGC,’ a plant-specific intron sequence PAGE
PBA Cytochrome P450-based analogue sequences Universal primers targeting the P450 genes AGE
TBP Β-Tubulim A single degenerate primer binds to the conserved introns of the β-tubulin. Polymorphism is based on varied intron length AGE
ITAP Intron/exon splice junctions In two primers-based amplification assays, one primer is derived from SRAP, and the other targets the intron/exon splice junction AGE
ISAP SINES Two primers-based amplification assays, designed with SINE elements to amplify the adjacent genomic regions AGE
SCAR Sequence-Specific clones Two primer-based amplification assays, with the primers derived from single loci clones from unique RAPD, AFLP bands AGE
SSAP Transposable elements Restriction digestion was followed by two primer amplifications, one LTR-specific and the other adapter-specific PAGE
iSNAP Small RNAs Two primer amplification assays, where primers are designed within and at the flanking regions of small RNAs mapped on the genome PAGE
PAAP Promoters Two primer-based amplification assays, with a plant-promoter-specific primer and an RAPD primer PAGE

AGE, agarose gel electrophoresis; PAGE, polyacrylamide gel electrophoresis.