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. 2024 Oct 17;15:1437558. doi: 10.3389/fneur.2024.1437558

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Copyright © 2024 Giffen, Liu, Yamane, Li, Chen, Kramer, Zallocchi and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein-coding gene orthologs expressed in zebrafish and mouse HCs. (A) Commonly and uniquely expressed protein-coding gene orthologs among zHC, and mouse IHC and OHC populations are shown in the Venn diagram. The number in parentheses indicates additional paralogous genes expressed only in zHCs. Representative images of isolated mouse IHC and OHC (10), and zebrafish HC are shown. (B) Bar graph shows the number of uniquely and commonly expressed gene orthologs among the HC populations. Volcano plots with number (n) of upregulated and downregulated genes in (C) zHC vs. IHC, (D) zHC vs. OHC, and (E) IHC vs. OHC (log2 fold change > 1.0; -log10 adjusted p-value < 0.05).