TABLE 11.

Skin microbiota related to development of cancer.

No	Studies	Outcomes	References
1	Investigating skin microbiome in squamos cell carcinoma (SCC) and premalignant actinic keratosis compared with healthy skin to identify skin cancer-associated changes in the skin microbiome from skin swabs. Overall 336 samples including patient with healthy skin (n = 138), actinic keratosis (n = 76), SCC (n = 93) and the controls patient with healthy skin (n = 29)	• For instance, the pathobiont Staphylococcus aureus was found to be increased at the expense of the commensal Cutibacterium acnes in SCC compared to healthy skin • The most discriminant genera were Cutibacterium (healthy skin-associated) and Staphylococcus (AK- and SCC-associated) • At the species level, multiple Lactobacillus species (e.g., L. rhamnosus and L. plantarum) were less abundant in AK and SCC, whereas Ralstonia, particularly R. pickettii, was positively associated with AK and SCC	Voigt et al. (2022)