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. 2024 Oct 17;5:1462569. doi: 10.3389/fragi.2024.1462569

TABLE 4.

Oral microbiota related to NAFLD.

No Studies Outcomes References
1 Reviewing the saliva microbiome in 10 NAFLD/MAFLD patients and 10 healthy patients using 16S rRNA amplicon sequencing and bioinformatics analysis - There was an increase in the relative abundance of Firmicutes and a decrease in Proteobacteria in the NAFLD group compared to the healthy group
- A panel detecting 7 genera, namely, Fretibacterium, Neisseria, Treponema, Delftia, Capnocytophaga, Dialister, and Erysipelotrichaceae_UCG-003, was identified as an optimal biomarker with an AUC of 0.82
- Alpha diversity, measured by the Ace and Chao1 richness indices, was significantly higher in the MAFLD group compared to the NAFLD group
Wang et al. (2023)
2 Reviewing the fungal microbiome in saliva, feces, and supragingival plaque in 21 NAFLD/MAFLD patients and 20 healthy patients using 16 S rRNA amplicon sequencing and bioinformatics analysis - Mucor ambiguus increased in saliva samples of MAFLD patients compared to controls Niu et al. (2023)