TABLE 4.
Oral microbiota related to NAFLD.
| No | Studies | Outcomes | References |
|---|---|---|---|
| 1 | Reviewing the saliva microbiome in 10 NAFLD/MAFLD patients and 10 healthy patients using 16S rRNA amplicon sequencing and bioinformatics analysis | - There was an increase in the relative abundance of Firmicutes and a decrease in Proteobacteria in the NAFLD group compared to the healthy group - A panel detecting 7 genera, namely, Fretibacterium, Neisseria, Treponema, Delftia, Capnocytophaga, Dialister, and Erysipelotrichaceae_UCG-003, was identified as an optimal biomarker with an AUC of 0.82 - Alpha diversity, measured by the Ace and Chao1 richness indices, was significantly higher in the MAFLD group compared to the NAFLD group |
Wang et al. (2023) |
| 2 | Reviewing the fungal microbiome in saliva, feces, and supragingival plaque in 21 NAFLD/MAFLD patients and 20 healthy patients using 16 S rRNA amplicon sequencing and bioinformatics analysis | - Mucor ambiguus increased in saliva samples of MAFLD patients compared to controls | Niu et al. (2023) |