Figure 3.

In vitro effects of bLf on subpopulations of NK and T cells from unexposed and COVID-19 groups. (A) Percentage of NK^bright (CD3⁻CD56^highCD16⁻), (B) NKT(CD3⁺CD56⁺), (C) CD4⁺ activated T cells (CD69⁺), (D) exhausted CD4⁺ T cells (PD-1⁺), and (E) exhausted CD8⁺ T (PD-1⁺) cells upon stimulation with different bLf concentrations (1, 5, and 10 mg/mL), as well as unstimulated (mock). Levels of (F) IL-6, (G) CXCL8 (IL-8), and (H) CCL5 (RANTES) detected in supernatant obtained from cell stimulation conditions. *p < 0.05 and **p < 0.01.