Table 2.
Characteristics of participants from the Framingham Heart Study and UK Biobank
| Covariate | UK Biobank (N = 46,434) Mean (SD)/N (%) | FHS (N = 1,886) Mean (SD)/N (%) |
|---|---|---|
| Age, years | 57 (8) | 55 (10.0) |
| <30 | 0 (0%) | 1 (0.1%) |
| 30–39 | 1 (<0.1%) | 108 (5.7%) |
| 40–49 | 10,145 (22%) | 506 (27%) |
| 50–59 | 14,597 (31%) | 601 (32%) |
| 60–69 | 21,381 (46%) | 527 (28%) |
| 70–79 | 310 (0.7%) | 139 (7.4%) |
| ≥80 | 0 (0%) | 4 (0.2%) |
| Female, n (%) | 25,361 (55) | 1,009 (54) |
| Non-Hispanic White, n (%) | 43,414 (93) | 1,864 (98.8) |
| Hispanic White, n (%) | N/A | 6 (0.32) |
| Black, n (%) | 1,009 (2.2) | 1 (0.05) |
| Asian, n (%) | 969 (2.1) | 1 (0.05) |
| Other race, n (%) | 1,042 (2.2) | 14 (0.75) |
| Body mass index, kg/m2 | 27.5 (4.8) | 27.4 (5.1) |
| BMI <25 | 14,756 (32%) | 662 (35%) |
| BMI ≥25 and <30 | 11,619 (25%) | 762 (40%) |
| BMI ≥30 | 19,817 (43%) | 462 (25%) |
| Current smoker, n (%) | 4,970 (11%) | 368 (20%) |
| Systolic blood pressure, mmHg | 140 (20) | 126 (19) |
| Systolic blood pressure ≥130 | 29,548 (64%) | 746 (40%) |
| Diabetes, n (%) | 2,686 (5.8%) | 145 (7.7%) |
| Cardiovascular disease, n (%) | 3,015 (6.5%) | 109 (5.8%) |
| Total cholesterol, mg/dL | N/A | 205 (36) |
| Total high-density lipoprotein cholesterol, mmol/L: UK Biobank, mg/dL: FHS | 1.44 (0.38) | 50 (15) |