Fig. 6.

In vivo anti-tumor evaluation. (A) The in vivo distribution of P-IR890. (B) Thermal images of 4T1 tumor bearing mice with different treatments. (C) The corresponding increasing temperature curve for treated mice. (D) Growth curves of 4T1 tumors for different groups. (E) Photographs of tumors with different treatments on Day 14. (scale bar: 1 cm) (F) The corresponding average tumor weight with different groups on Day 14. (G) Representative images of H&E and TUNEL stained tumor sections from each treated group. The blue arrows indicated the necrosis of cancer cells. (Scale bar: 100 µm). ^⁎⁎P < 0.01, ^⁎⁎⁎P < 0.001. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)