Skip to main content
. 2024 Oct 15;9(43):43557–43569. doi: 10.1021/acsomega.4c05459

Figure 7.

Figure 7

Interaction site of the ligand (quinoline dione) with receptors. The figure illustrates the interactions between quinoline dione and different protein targets as identified by their PDB IDs: 1RO5, 3D5K, and 6MVN. Interaction with 1RO5: quinoline dione interacts primarily through van der Waals forces. Key residues involved include THR A:144, THR A:145, ARG A:30, PHE A:105, ALA A:106, VAL A:26, ILE A:107, and VAL A:148. Interaction with 3D5K: The interaction involves both van der Waals forces and conventional hydrogen bonds. Notable residues participating in the interaction include ALA C:216, PHE C:422, GLN C:426 (hydrogen bond), GLN C:418, ALA C:212, TYR C:185, and LEU A:389. Interaction with 6MVN: This interaction is characterized by van der Waals forces, conventional hydrogen bonds, and carbon hydrogen bonds. Significant residues include HIS A:63, LYS B:16 (hydrogen bond), ARG A:66 (hydrogen bond), GLU A:62 (carbon hydrogen bond), PHE B:51, and ALA B:50.