| Procedure details |
|
|
|
| Transfemoral approach |
13 239/13 844 (95.6) |
119 908/125 830 (95.3) |
.08 |
| Type of anesthesia, moderate sedation |
7507/13 840 (54.2) |
72 629/125 722 (57.8) |
<.001 |
| Total procedure time, mean (SD), min |
71.5 (41.4) |
68.6 (39.7) |
<.001 |
| Fluoroscopy time, mean (SD), min |
14.5 (10.9) |
14.1 (9.7) |
<.001 |
| Contrast volume, mean (SD), mL |
91.0 (57.6) |
85.5 (52.1) |
<.001 |
| Implant success |
13 750/13 845 (99.3) |
124 809/125 821 (99.2) |
.14 |
| Conversion to open heart surgery |
30/13 828 (0.2) |
302/125 712 (0.2) |
.59 |
| Procedure status |
|
|
|
| Elective |
11 747/13 848 (84.8) |
114 919/125 823 (91.3) |
<.001 |
| Urgent/emergency/salvage |
2101/13 848 (15.2) |
10 904/125 823 (8.7) |
| Heart team reason for procedure |
|
|
|
| Inoperable/extreme risk |
761/13 763 (5.5) |
4402/125 124 (3.5) |
<.001 |
| High risk |
3907/13 763 (28.4) |
28 936/125 124 (23.1) |
<.001 |
| Intermediate risk |
3634/13 763 (26.4) |
41 929/125 124 (33.5) |
<.001 |
| Low risk |
5461/13 763 (39.7) |
49 857/125 124 (39.8) |
.70 |
| Procedure complication |
|
|
|
| Annular dissection |
14/13 849 (0.1) |
140/125 846 (0.1) |
.73 |
| Aortic dissection |
13/13 849 (0.1) |
96/125 846 (0.1) |
.48 |
| Coronary compression or obstruction |
16/13 849 (0.1) |
102/125 846 (0.1) |
.19 |
| Device embolization |
3/13 849 (0.0) |
149/125 846 (0.1) |
.001 |
| Perforation with or without tamponade |
33/13 849 (0.2) |
515/125 846 (0.4) |
.002 |
| THV size |
|
|
|
| 20 mm |
177/13 844 (1.3) |
2330/125 799 (1.9) |
<.001 |
| 23 mm |
3340/13 844 (24.1) |
37 492/125 799 (29.8) |
<.001 |
| 26 mm |
6252/13 844 (45.2) |
56 283/125 799 (44.7) |
.35 |
| 29 mm |
4075/13 844 (29.4) |
29 694/125 799 (23.6) |
<.001 |
| In-hospital outcomes |
|
|
|
| Index hospitalization length of stay, median (IQR), d |
1.0 (1.0-2.0) |
1.0 (1.0-2.0) |
<.001 |
| ICU length of stay, mean (SD), h |
20.5 (53.7) |
17.8 (42.8) |
.002 |
| Discharge to home |
13 092/13 848 (94.5) |
119 309/125 838 (94.8) |
.17 |
| All-cause mortality |
133/13 849 (1.0) |
930/125 846 (0.7) |
.004 |
| Cardiac death |
93/13 849 (0.7) |
581/125 846 (0.5) |
<.001 |
| Stroke |
118/13 849 (0.9) |
1272/125 846 (1.0) |
.07 |
| Aortic valve reintervention |
8/13 849 (0.1) |
95/125 846 (0.1) |
.47 |
| Life-threatening bleeding, derived |
133/13 849 (1.0) |
1052/125 846 (0.8) |
.13 |
| Major vascular complication |
110/13 849 (0.8) |
1242/125 846 (1.0) |
.03 |
| New requirement for dialysis |
40/13 849 (0.3) |
323/125 846 (0.3) |
.48 |
| New pacemaker without baseline pacemaker |
566/13 268 (4.3) |
6519/116 999 (5.6) |
<.001 |
| Any readmissions |
29/13 849 (0.2) |
250/125 846 (0.2) |
.79 |
| New onset of atrial fibrillation |
145/11 937 (1.2) |
1572/99 182 (1.6) |
.002 |
