Fig. 5.

Structural covariance of hypothalamic volume (HV) with cortical thickness (CTH) and gray matter volume (GMV) depending on apolipoprotein E (APOE) ε4-allele carriership. Numbers indicate location on the z axis and colour indicates t-score value. ε4 = 1 homo- or heterozygous carriership of APOE ε4-allele, ε4 = 0 no APOE ε4-allele carriership. Results of CTH analyses are illustrated at p < 0.05 family-wise error (FWE) voxel-level corrected and k = 10. Voxel-based morphometry (VBM) GMV analyses are illustrated at a liberal, uncorrected threshold of p < 0.001 and k = 100.