Table 2.
|
Eradication rate
|
P value
|
||
500 mg bid (n = 73)
|
500 mg tid (n = 74)
|
750 mg bid (n = 71)
|
||
All | 65, 89.0% | 61, 82.4% | 56, 78.9% | 0.25 |
Primary therapy | 54/60, 90.0% | 37/42, 88.1% | 14/16, 87.5% | 0.85 |
1 prior therapy | 8/8, 100% | 22/27, 81.5% | 27/39, 69.2% | |
≥ 2 prior therapies | 3/5, 60.0% | 2/5, 40.0% | 15/16, 93.8% | |
Rescue therapy1 | 11/13, 84.6% | 24/32, 75.0% | 42/55 76.4% | 0.89 |
Rescue therapy was defined as patients who had received eradication therapy once or more but failed.
P values were from two-sided comparisons of the differences between the three groups. 500 mg bid: Tetracycline twice daily; 500 mg tid: Tetracycline three times daily; 750 mg bid: Tetracycline twice daily.